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Links to some of the latest research and articles on
binge-eating, food addiction, and related topics

 

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Brain-neuroscience related information

 

Fatty food bad for you?  It may be a no-brainer

Postmedia News (Dec. 28, 2011) by Sharon Kirkey – Researchers have found that there’s a part of your body that might actually shrink when you eat too much fast food. Unfortunately, it’s your brain. People with diets high in trans fats are more likely to experience the kind of brain shrinkage associated with Alzheimer’s disease than people who consume less of the artery-damaging fats, the new study suggests.  http://news.nationalpost.com/2011/12/28/fatty-food-bad-for-you-it-may-be-a-no-brainer/

 

Could obesity change the brain? 

NPR's Health Blog: Shots (Dec.28, 2011) by Nancy Shute – The standard advice for losing weight often comes up short for people who are obese. If they switch to a healthful diet and exercise more, they might lose a bit. But the pounds have a way of creeping back on. Now some provocative research suggests that a part of the problem might be that obesity could change the area of the brain that helps control appetite and body weight. http://www.npr.org/blogs/health/2011/12/27/144331177/could-obesity-change-the-brain?ft=1&f=1128&sc=tw

 

New map shows where tastes are coded in the brain

ScienceDaily (Sep. 5, 2011) — Each taste, from sweet to salty, is sensed by a unique set of neurons in the brains of mice, new research reveals. The findings demonstrate that neurons that respond to specific tastes are arranged discretely in what the scientists call a "gustotopic map." This is the first map that shows how taste is represented in the mammalian brain.

http://www.sciencedaily.com/releases/2011/09/110901142110.htm

 

Free radicals crucial to suppressing appetite

ScienceDaily (Aug. 29, 2011) — Obesity is growing at alarming rates worldwide, and the biggest culprit is overeating. In a study of brain circuits that control hunger and satiety, Yale School of Medicine researchers have found that molecular mechanisms controlling free radicals -- molecules tied to aging and tissue damage -- are at the heart of increased appetite in diet-induced obesity.

http://www.sciencedaily.com/releases/2011/08/110828140931.htm

 

Do you eat when you’re stressed? This new study knows why

Globe and Mail (Aug. 11, 2011), by Dawn Walton – A new Canadian study has pinpointed how stress can temporarily rewire the nerve cells in the brain to ramp up hunger pangs. The findings finally put some science behind what people have thought for years.  http://www.theglobeandmail.com/life/health/new-health/health-nutrition/nutrition-features/do-you-eat-when-youre-stressed-this-new-study-knows-why/article2126896/

 

Salt appetite is linked to drug addiction, research finds

ScienceDaily (July 29, 2011) — A team of Duke University Medical Center and Australian scientists has found that addictive drugs may have hijacked the same nerve cells and connections in the brain that serve a powerful, ancient instinct: the appetite for salt.  http://www.sciencedaily.com/releases/2011/07/110711151451.htm#.TjghwVk0fJM.email

 

Does food act physiologically like a 'drug of choice' for some?

ScienceDaily (July 20, 2011) — Variety is considered the "spice of life," but does today's unprecedented level of dietary variety help explain skyrocketing rates of obesity? Some researchers think it might.  According to ASN Spokesperson Shelley McGuire, PhD: "We've known for years that foods- even eating, itself- can trigger release of various brain chemicals, some of which are also involved in what happens with drug addiction and withdrawal. And, as can happen with substance abusers, tolerance or "habituation" can occur, meaning that repeated use (in this case, exposure to a food) is sometimes accompanied by a lack of response (in this case, disinterest in the food). The results of the study by Epstein and colleagues provides a very interesting new piece to the obesity puzzle by suggesting that meal monotony may actually lead to reduced calorie consumption. The trick will be balancing this concept with the importance of variety to good nutrition."  http://www.sciencedaily.com/releases/2011/07/110719114340.htm

 

Eat a protein-rich breakfast to reduce food cravings, prevent overeating later, researcher finds

ScienceDaily (May 19, 2011) — A University of Missouri researcher has found that eating a healthy breakfast, especially one high in protein, increases satiety and reduces hunger throughout the day. In addition, using functional magnetic resonance imaging (fMRI) the researchers found that eating a protein-rich breakfast reduces the brain signals controlling food motivation and reward-driven eating behavior.

http://www.sciencedaily.com/releases/2011/05/110519113024.htm

 

Food addiction works like drug addiction in the brain

Huffington Post (Apr. 5, 2011) – Seeing a milkshake can activate the same areas of the brain that light up when an addict sees cocaine, U.S. researchers said on Monday. The study helps explain why it can be so hard for some people to maintain a healthy weight, and why it has been so difficult for drug makers and health experts to find obesity treatments that work.  http://www.huffingtonpost.com/2011/04/05/food-addiction-brain_n_844931.html

 

Binge eaters' dopamine levels spike at sight, smell of food

ScienceDaily (Feb. 28, 2011) — A brain imaging study at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory reveals a subtle difference between ordinary obese subjects and those who compulsively overeat, or binge: In binge eaters but not ordinary obese subjects, the mere sight or smell of favorite foods triggers a spike in dopamine -- a brain chemical linked to reward and motivation. 
http://www.sciencedaily.com/releases/2011/02/110228104308.htm

 

Hand study reveals brain's distorted body model 

ScienceDaily (June 16, 2010) — Our brains contain a highly distorted model of our own bodies, according to scientists at UCL (University College London)
http://www.sciencedaily.com/releases/2010/06/100614160201.htm

 

Obesity gene, carried by more than a third of the us population, leads to brain tissue loss
ScienceDaily
(Apr. 20, 2010) — Three years ago, geneticists reported the startling discovery that nearly half of all people in the U.S. with European ancestry carry a variant of the fat mass and obesity associated (FTO) gene, which causes them to gain weight -- from three to seven pounds, on average -- but worse, puts them at risk for obesity.  
http://www.sciencedaily.com/releases/2010/04/100419162308.htm?sms_ss=email

 

Fear of getting fat seen in healthy women's brain scans 

ScienceDaily (Apr. 14, 2010) — A group of women in a new study seemed unlikely to have body image issues -- at least their responses on a tried-and-true psychological screening presented no red flags. That assessment changed when Brigham Young University researchers used MRI technology to observe what happened in the brain when people viewed images of complete strangers.  http://www.sciencedaily.com/releases/2010/04/100413151913.htm

 

Rats with part of brain deactivated move toward food but do not eat 

ScienceDaily (Sep. 9, 2009) — Scientists led a rat to the fatty food, but they couldn’t make it eat. Using an animal model of binge eating, University of Missouri researchers discovered that deactivating the basolateral amygdala, a brain region involved in regulating emotion, specifically blocked consumption of a fatty diet. Surprisingly, it had no effect on the rat wanting to look for the food repeatedly. “It appears that two different brain circuits control the motivation to seek and consume,” said Matthew Will, assistant professor of psychological sciences in the MU College of Arts and Science and investigator in the Christopher S. Bond Life Sciences Center.

http://www.sciencedaily.com/releases/2009/09/090908151334.htm

 

Why some continue to eat when full: Researchers find clues

ScienceDaily (Dec. 28, 2009) — The premise that hunger makes food look more appealing is a widely held belief -- just ask those who cruise grocery store aisles on an empty stomach, only to go home with a full basket and an empty wallet.  Prior research studies have suggested that the so-called hunger hormone ghrelin, which the body produces when it's hungry, might act on the brain to trigger this behavior. New research in mice by UT Southwestern Medical Center scientists suggest that ghrelin might also work in the brain to make some people keep eating "pleasurable" foods when they're already full.

http://www.sciencedaily.com/releases/2009/12/091228090539.htm

 

Dopamine enhances expectation of pleasure in humans

ScienceDaily (Nov. 15, 2009) — Enhancing the effects of the brain chemical dopamine influences how people make life choices by affecting expectations of pleasure, according to new research from the UCL Institute of Neurology.  The study, published in Current Biology, confirms an important role for dopamine in how human expectations are formed and how people make complex decisions. It also contributes to an understanding of how pleasure expectation can go awry, for example in drug addiction.

http://www.sciencedaily.com/releases/2009/11/091112121603.htm

 

Scientists identify stomach’s timekeepers of hunger

ScienceDaily (Aug. 31, 2009) — New York collaborators at Columbia and Rockefeller Universities have identified cells in the stomach that time the release of a hormone that makes animals anticipate food and eat even when they are not hungry. The finding, which has implications for the treatment of obesity, marks a landmark in the decades-long search for the timekeepers of hunger. The work reveals what the stomach “tells” the brain.

http://www.sciencedaily.com/releases/2009/08/090829092042.htm

 

High-fat, high-sugar foods alter brain receptors

ScienceDaily (Aug. 6, 2009) — Over consumption of fatty, sugary foods leads to changes in brain receptors, according to new animal research at Johns Hopkins University School of Medicine.  The new research results are being presented at the 2009 annual meeting of the Society for the Study of Ingestive Behavior (SSIB). The results have implications for understanding bulimia and other binge eating disorders.  http://www.sciencedaily.com/releases/2009/07/090727102024.htm

 

8 ways the food industry hijacks your brain:  Overeating doesn't only affect people who are overweight

msnbc.com (July 10, 2009) — In the 21st century the food industry is creating and marketing unhealthy food in much the same way that tobacco companies manufactured and sold cigarettes in the 20th century… more than 70 million Americans have become conditioned to overeat, and it affects people of all different weights. Dr. David A. Kessler, the dynamic and controversial former head of the Food and Drug Administration who took on big tobacco in the 1990s, now takes on the food industry …[and] pulls back the curtain to reveal how the food industry and its scientists really operate.

http://www.msnbc.msn.com/id/31832558/ns/health-diet_and_nutrition/

 

Finding fear: Neuroscientists locate where it is stored in the brain

ScienceDaily (July 8, 2009) — Fear is a powerful emotion, and neuroscientists have for the first time located the neurons responsible for fear conditioning in the mammalian brain. Fear conditioning is a form of Pavlovian, or associative, learning and is considered to be a model system for understanding human phobias, post-traumatic stress disorder and other anxiety disorders.  http://www.sciencedaily.com/releases/2009/07/090707093753.htm

 

A biology of mental disorder

Newsweek (June 27, 2009, from the July 13, 2009 magazine issue) by Eric Kandel — Understanding the biology of mental illness would be a paradigm shift in our thinking about mind…The most convincing scientific progress in psychiatry in the past decade has had little to do with genomics. It is the rigorous, scientific verification that certain forms of psychotherapy are effective. This is perhaps not surprising. One of the major insights in the modern biology of learning and memory is that education, experience, and social interactions affect the brain.  http://www.newsweek.com/id/204320

 

How the food makers captured our brains

New York Times (June 22, 2009) by Tara Parker-Pope – As head of the Food and Drug Administration, Dr. David A. Kessler served two presidents and battled Congress and Big Tobacco. But the Harvard-educated pediatrician discovered he was helpless against the forces of a chocolate chip cookie…The result of Dr. Kessler’s quest is a fascinating new book, “The End of Overeating: Taking Control of the Insatiable American Appetite” (Rodale).

http://www.nytimes.com/2009/06/23/health/23well.html?_r=1&ref=health

 

Flipping the brain's addiction switch without drugs 

ScienceDaily (May 29, 2009) — When someone becomes dependent on drugs or alcohol, the brain's pleasure center gets hijacked, disrupting the normal functioning of its reward circuitry.  Researchers investigating this addiction "switch" have now implicated a naturally occurring protein, a dose of which allowed them to get rats hooked with no drugs at all.

http://www.sciencedaily.com/releases/2009/05/090528142825.htm

 

Brain's organization switches as children become adults

ScienceDaily (May 17, 2009) — Any child confronting an outraged parent demanding to know "What were you thinking?" now has a new response: "Scientists have discovered that my brain is organized differently from yours."  http://www.sciencedaily.com/releases/2009/05/090515093228.htm

 

Blow your diet? Blame your brain:  low-fat labels and encouraging exercise can backfire  

msnbc.com (May 13, 2009) by Linda Carroll — Ever make a resolution to go out and exercise and end up grabbing a gooey chocolate cupcake instead?  No matter how good our intentions are, sometimes it seems like our stomachs are out to sabotage us. Scientists are now starting to understand why this happens.   http://www.msnbc.msn.com/id/30702871/

 

Brain's problem-solving function at work when we daydream

ScienceDaily (May 12, 2009) — A new University of British Columbia study finds that our brains are much more active when we daydream than previously thought.  The study, published in the Proceedings of the National Academy of Sciences, finds that activity in numerous brain regions increases when our minds wander. It also finds that brain areas associated with complex problem-solving – previously thought to go dormant when we daydream – are in fact highly active during these episodes.   http://www.sciencedaily.com/releases/2009/05/090511180702.htm

 

Brain chemical reduces anxiety, increases survival of new cells

ScienceDaily (May 13, 2009) — New research on a brain chemical involved in development sheds light on why some individuals may be predisposed to anxiety. It also strengthens understanding of cellular processes that may be common to anxiety and depression, and suggests how lifestyle changes may help overcome both.

http://www.sciencedaily.com/releases/2009/05/090512193229.htm

 

Can't curb your enthusiasm for food? Blame the brain

CBC News (Apr. 30, 2009) — Next time you give in to that craving for a chocolate bar as your energy levels take a mid-afternoon dip, you could be justified in saying that your brain made you do it. A new study published in the May 1 issue of the journal Science concluded there are differences in the brains of people who are good at controlling their urges versus those who find it almost impossible . . .The research was conducted by scientists at the California Institute of Technology. The study involved dieters, but the scientists say their findings could also be applied to addictions, illegal behaviour and risky financial decisions since each involves willpower.   http://www.cbc.ca/health/story/2009/04/30/blamethebrain.html

 

Dieters' best intentions hijacked by their brains

msnbc.com (Apr. 20, 2009) — New research suggests millions have their best intentions foiled by "conditioned hypereating" - the drive to eat high-fat, high-sugar foods even when they're not hungry.  http://www.msnbc.msn.com/id/30312808/from/ET/

 

Human brains make their own 'marijuana'

ScienceDaily (Apr. 20, 2009) — U.S. and Brazilian scientists have discovered that the brain manufactures proteins that act like marijuana at specific receptors in the brain itself. This discovery may lead to new marijuana-like drugs for managing pain, stimulating appetite, and preventing marijuana abuse.

http://www.sciencedaily.com/releases/2009/04/090420151240.htm

 

Early brain marker for familial form of depression: Structural changes in brain's cortex

ScienceDaily (Mar. 26, 2009) — Findings from one of the largest-ever imaging studies of depression indicate that a structural difference in the brain – a thinning of the right hemisphere – appears to be linked to a higher risk for depression, according to new research at Columbia University Medical Center and the New York State Psychiatric Institute.

http://www.sciencedaily.com/releases/2009/03/090324081437.htm

 

Scars of child abuse reach down to genetic level, scientists find

cbc.ca (Feb 23, 2009) — Child abuse early in life appears to permanently change how people respond to stress, say researchers in Montreal who studied the brains of suicide victims.
Copyright 2009 CBC All Rights Reserved
http://www.cbc.ca/health/story/2009/02/23/child-abuse-brain.html

 

Study: Men's brains fight food urges better,

cnn.com / Health (Jan. 19, 2009) by Anne Harding — PET scans of brains of 23 people were observed, while they looked at favorite foods.   Women's brain activity didn't change when asked to suppress desire.  Men showed less activation in brain involved in emotional regulation and motivation.  Men may have better tools for appetite control

http://www.emailthis.clickability.com/et/emailThis?clickMap=viewThis&etMailToID=1845225782

 

Fit older women have better brain function: Study

Thestar.com / The Canadian Press (Jan. 8, 2009) by Sheryl Ubelacker  — Regular physical activity is known to improve cognitive ability and help stave off dementia, and now Canadian researchers think they know why.   http://www.healthzone.ca/health/article/564221

 

Brain circuit abnormalities may underlie bulimia nervosa in women

ScienceDaily (Jan. 7, 2009) — Women with bulimia nervosa appear to respond more impulsively during psychological testing than those without eating disorders, and brain scans show differences in areas responsible for regulating behavior, according to a new report.

http://www.sciencedaily.com/releases/2009/01/090105175031.htm

 

Brain enzyme may play key role in controlling appetite and weight gain

ScienceDaily (Dec. 16, 2008) — Researchers at Albert Einstein College of Medicine of Yeshiva University have found that overactivity of a brain enzyme may play a role in preventing weight gain and obesity. The findings were reported in Cell Metabolism.

http://www.sciencedaily.com/releases/2008/12/081212141845.htm

 

Obesity all in your head? Brain genes associated with increased body mass

ScienceDaily (Dec. 15, 2008) — Is obesity all in your head? New research suggests that genes that predispose people to obesity act in the brain and that perhaps some people are simply hardwired to overeat.

http://www.sciencedaily.com/releases/2008/12/081214190959.htm

 

Study: Six new gene mutations linked to obesity

msnbc.com (Dec. 14, 2008) — Researchers have identified six new gene mutations linked to obesity and said on Sunday they point to ways the brain and nervous system control eating and metabolism.  http://www.msnbc.msn.com/id/28222722/from/ET/

 

Sugar can be addictive: animal studies show sugar dependence

ScienceDaily (Dec. 11, 2008) — A Princeton University scientist will present new evidence today demonstrating that sugar can be an addictive substance, wielding its power over the brains of lab animals in a manner similar to many drugs of abuse.

http://www.sciencedaily.com/releases/2008/12/081210090819.htm

 

For the overweight, bad advice by the spoonful

New York Times (Aug. 30, 2007) by Gina Kolata —Two-thirds of Americans are overweight or obese. For most, research shows, neither diets nor moderate exercise brings significant long-term weight loss.  In brief:  weight control is not simply a matter of willpower; genes help determine the body's "set point," which is defended by the brain; dieting alone is rarely successful, and relapse rates are high; moderate exercise, too, rarely results in substantive long-term weight loss, which requires intensive exercise.

http://health.nytimes.com/ref/health/healthguide/esn-obesity-ess.html

 

This is your brain on chocolate

New York Times  (Aug.  23, 2005) by Donald G. McNeil Jr. — You remember Isaac Newton, his apple and the "Why didn't it fall up?" question. In the olfactory sciences, a crucial line of inquiry was opened up some years ago when a friend of a psychologist who was studying food asked, "If I hate the smell of Limburger cheese, why is it so delicious?"  Researchers at Yale, the John B. Pierce Laboratory and the University of Dresden may now be closer to a biological answer.  They got 11 volunteers to lie inside magnetic brain scanners . . . Four odours were pumped in: butanol, farnesol (both described as "pleasantly musky"), lavender and chocolate.  Only chocolate activated two different regions. Smelled from up front, it lighted up pleasure-anticipation neurons; from the back, it lighted up food-reward neurons.

http://www.nytimes.com/2005/08/23/science/23nose.html?pagewanted=print

 

Studies on the dopamine connection
CBC Marketplace: Food/Junk Food Addiction
(Oct. 29, 2002) by Reporter: Wendy Mesley; Producer: Greg Sadler; Researchers: Colman Jones, Leonardo Palleja  Scientists at the Department of Energy's Brookhaven National Laboratory found that dopamine, a brain chemical associated with addiction to cocaine, alcohol, and other drugs, may also play an important role in obesity.   http://www.cbc.ca/consumers/market/files/food/junkfood_addiction/dopamine.html

 

Measuring brain activity in people eating chocolate offers new clues about how the body becomes addicted

ScienceDaily (Aug. 29, 2001) — Using positron emission tomography scans to measure brain activity in people eating chocolate, a team of U.S. and Canadian neuroscientists believe they have identified areas of the brain that may underlie addiction and eating disorders.

http://www.sciencedaily.com/releases/2001/08/010829082943.htm

 

Brain chemicals may cause bulimia

BBC online: Health  (October 14, 1998) — The eating disorder bulimia nervosa may be caused, at least in part, by chemical changes to the brain, researchers have discovered.  Scientists have found that chemical changes that take place in the brains of sufferers persist even after recovery.

http://news.bbc.co.uk/2/hi/health/192727.stm

 

published by: changehappens.ca

last updated:  Jan. 29, 2012

 

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